The increased circulation of NEFAs leads to triacyl glyceride synthesis later deposited in the liver. To handle the excessive NEFA availability L-carnitine is needed which is essential to transfer fatty acids into the mitochondria for their oxidation.
Dairy cows require glucose during lactation for milk synthesis and maintenance of body tissues. Ruminal degradation of soluble sugars and starches into volatile fatty acids limits the amount of glucose that can be absorbed in the small intestine. This may limit milk synthesis and reproductive performance during the lactation